Search on: CARCINOMA, MERKEL CELL 
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Descriptor English:   Carcinoma, Merkel Cell 
Descriptor Spanish:   Carcinoma de Células de Merkel 
Descriptor Portuguese:   Carcinoma de Célula de Merkel 
Synonyms English:   Merkel Cell Tumor  
Tree Number:   C02.256.721.150
C02.928.216
C04.557.465.625.650.240.325
C04.557.470.200.025.370.325
C04.557.580.625.650.240.325
Definition English:   A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245) 
Indexing Annotation English:   coordinate IM with SKIN NEOPLASMS (IM)
History Note English:   89; CARCINOMA, TRABECULAR was see CARCINOMA, MERKEL CELL 1992-93 
Allowable Qualifiers English:  
BS blood supply BL blood
CF cerebrospinal fluid CI chemically induced
CH chemistry CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SC secondary
SE secretion SU surgery
TH therapy US ultrasonography
UL ultrastructure UR urine
VE veterinary VI virology
Record Number:   23573 
Unique Identifier:   D015266 

Occurrence in VHL:
 

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